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[1]王超,邓秋林,陈超,等.微反应器中硝酸氧化乙二醛制备乙醛酸[J].南京工业大学学报(自然科学版),2018,40(01):66-73.[doi:10.3969/j.issn.1671-7627.2018.01.011]
 WANG Chao,DENG Qiulin,CHEN Chao,et al.Preparation of glyoxylic acid through oxidation of glyoxal with HNO3 in a microreactor[J].Journal of NANJING TECH UNIVERSITY(NATURAL SCIENCE EDITION),2018,40(01):66-73.[doi:10.3969/j.issn.1671-7627.2018.01.011]
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微反应器中硝酸氧化乙二醛制备乙醛酸()
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《南京工业大学学报(自然科学版)》[ISSN:1671-7627/CN:32-1670/N]

卷:
40
期数:
2018年01期
页码:
66-73
栏目:
出版日期:
2018-01-20

文章信息/Info

Title:
Preparation of glyoxylic acid through oxidation of glyoxal with HNO3 in a microreactor
文章编号:
1671-7627(2018)01-0066-08
作者:
王超1邓秋林2陈超1沈如伟1张利雄1
1. 南京工业大学 化工学院 材料化学工程国家重点实验室,江苏 南京 210009; 2. 西南科技大学 材料科学与工程学院,四川 绵阳 621000
Author(s):
WANG Chao1DENG Qiulin2CHEN Chao1SHEN Ruwei1ZHANG Lixiong1
1.State Key Laboratory of Materials-Oriented Chemical Engineering,College of Chemical Engineering,Nanjing Tech University,Nanjing 210009,China; 2.School of Materials Science and Engineering, Southwest University of Science and Technology,Mianyang 621000,China
关键词:
微反应器 降膜微反应器 乙二醛 乙醛酸 氧化
Keywords:
microreactor falling film microreactor glyoxal glyoxylic acid oxidation
分类号:
TQ216
DOI:
10.3969/j.issn.1671-7627.2018.01.011
文献标志码:
A
摘要:
针对传统硝酸氧化乙二醛制备乙醛酸存在周期长、选择性低等问题,本文提出了一种在微反应器中高选择性合成乙醛酸的方法。先将35%硝酸与40%乙二醛按照一定摩尔比输送到T形微混合器,在微通道和降膜微反应器中反应一段时间,将得到的乙醛酸反应液再和硝酸以一定摩尔比输送到T形微混合器、微通道以及降膜微反应器中,循环几次后得到最终反应液。结果表明:当硝酸(流速0.13 mL/min)与乙二醛(流速0.24 mL/min)初次混合的摩尔比为0.42:1、硝酸(流速0.02 mL/min)与收集的乙醛酸反应液(流速0.24 mL/min)混合反应6次、T形微混合器与微通道的温度和停留时间分别为60 ℃和2 min、降膜微反应器反应温度为90 ℃时,乙二醛转化率为82%,乙醛酸选择性可达95%。
Abstract:
To solve the problems such as long production time and low selectivity in traditional methods for the preparation of glyoxylic acid from the oxidation of glyoxal,a modified synthesis by taking advantage of the microreactor was developed.35% nitric acid and 40% glyoxal of a certain ratio were mixed in a T-micromixer,and the mixture was passed by the microchannel and the falling film microreactor for a certain residence time.The resultant solutions were mixed with nitric acid in a certain ratio again.After several cycles,the glyoxylic acid reaction solutions were obtained.Results showed that the conversion rate of glyoxal and the glyoxylic acid selectivity could reach 82% and 95% when the reaction was performed by a procedure with six cycles under the following conditions:initial mixture molar ratio of nitric acid(0.13 mL/min)to glyoxal(0.24 mL/min)of 0.42:1,the flow rate of glyoxylic acid reaction solutions of 0.24 mL/min,the flow rate of nitric acid of 0.02 mL/min,the residence time and reaction temperature in the T-micromixer and microchannel of 2 min and 60 ℃,and the reaction temperature in the falling film microreactor of 90 ℃.

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备注/Memo

备注/Memo:
收稿日期:2016-05-03
基金项目:国家科技支撑计划(2015BAD15B00)
作者简介:王超(1990—),男,山东枣庄人,硕士,主要研究方向为微结构反应器在有机合成中的应用; 张利雄(联系人),教授,E-mail:lxzhangnjut@gmail.com.
引用本文:王超,邓秋林,陈超,等.微反应器中硝酸氧化乙二醛制备乙醛酸[J].南京工业大学学报(自然科学版),2018,40(1):66-73..
更新日期/Last Update: 2018-01-18